For lesions that are clearly on one side of the vulva, a radical local excision with a complete groin node dissection on the same side is performed. For other Stage I cancers involving the skin between the vaginal opening or the anus or clitoris, a radical vulvectomy and groin lymph node dissection on both sides is performed. Five-Year Survival Over 90 percent Investigational Conservative surgery. • Treatment with radiation therapy with or without chemotherapy (5-FU + mitomycin-C + cisplatin). Stage II TNM T2, N0, M0 The tumor is confined to the vulva and/or perineum and is more than 3/4 in. (2 cm) in diameter but has not spread to lymph nodes . Standard Treatment Radical vulvectomy with removal of the groin lymph nodes on both sides.